Histalim is a service provider company in histology, immunohistochemistry (IHC), in situ hybridization (ISH), and image analysis. Our laboratory located in Montpellier was founded in 2005. This positioning shows our willingness to meet the increasing demand to design, develop, and validate protocols based on standard and/or innovative techniques.
Our specialized services take part in research and development projects for pharmaceutic products, medical devices, and diagnostic tools… and in other domains like dermo-cosmetic, ecotoxicity, food industry… We are particularly engaged in the development of new therapies in the domains of oncology and chronic diseases i.e. therapeutic antibody, and new generation diagnostic tools i.e. circulating biomarkers. Histalim positions its strategic growth specifically in the development of therapeutic antibodies issues.
Our activities are conformed to Good Laboratory Practices (GLP) and our laboratory is authorized to perform studies with human tissue samples. Histalim can also offer to perform in-house research and development projects. This particularity allows us to provide some customized services to our customers, with innovative technologies. Therefore we can provide a large range of expert services like Tissue Cross Reactivity (TCR) studies, Tissue MicroArray (TMA), and Fluorescent ISH (FISH)…
MUC2 immunolabeling of rat colon is usefull to study the épithelium secretory defense against pathogen
Mainly used to demonstrate the presence of endothelial cells, it can determine the degree of angiogenesis, for example.
Classification of different levels of hepatic fibrosis according to the amount of collagen (red).
Tissue MicroArray (TMA) of a mouse tumor panel (Ki67).
Detection of cartilaginous structures into the bronchial walls.
Staining of stomach, small bowel and large bowel.
Von Kossa staining highlights calcium phosphates and carbonates in tissues (black staining). The counterstaining labels nuclei in red and cytoplasm in pink
HE alcian blue staining highlights acid mucopolysaccharides and mucins in blue.
Alcian blue staining highlights cartilage in blue.
PAS methenamine staining highlights the glomerular membranes (black staining).
The filaggrin is an epidermal protein associated with the maintenance of skin moisture in the stratum corneum.
Masson trichrome staining on mouse kidney
Immunogenicity characterization of human ureter in frozen block with CD31 immunostaining.
Immunogenicity characterization of human spinal cord with CD31 immunostaining.
Hematoxylin eosin staining of mouse sternum in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).
Immunogenicity characterization of human cerebellum in frozen block with CD31 immunostaining.
This histological marker of various potentially tumor tissues, is an ideal candidate for oncology diagnosis.
Hematoxylin eosin staining of mouse lung in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).
Hematoxylin eosin staining of mouse mandibular lymph nodes – salivary glands in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).
Hematoxylin eosin staining of mouse heart in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).
Hematoxylin eosin staining of mouse spleen – thymus – pancreas in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).
Hematoxylin eosin staining of mouse liver – adrenal glands in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).
Hematoxylin eosin staining of mouse stomac – duodenum – ileon – caecum – settler – rectum in the toxicity study in compliance with RITA.
Hematoxylin eosin staining of mouse tong – skeletal muscle – sciatic nerves in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).moelle-osseuse-multiplex