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Histology meeting

Histology meeting The IHC Multiplex Meeting was held at HISTALIM [...]

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HISTALIM will develop its own precision medicine tool named HISTOPROFILE

HISTALIM will develop its own precision medicine tool named [...]

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Domenico LAZZARO, M.D pathologist, joins Histalim!

Domenico LAZZARO, M.D pathologist, joins [...]

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How Histology can help injectable medical devices validity?

How Histology can help injectable medical devices validity? Injectable [...]

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HISTALIM

126, rue Emile Baudot
34000, Montpellier
FRANCE
+33 (0)4 67 712 765
contact@histalim.com

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MUC2 immunolabeling of rat colon

MUC2 immunolabeling of rat colon is usefull to study the épithelium secretory defense against pathogen

CD31 immunolabeling on human skin

Mainly used to demonstrate the presence of endothelial cells, it can determine the degree of angiogenesis, for example.

Sirius red staining on human liver

Classification of different levels of hepatic fibrosis according to the amount of collagen (red).

Tissue MicroArray (TMA) of a mouse tumor panel

Tissue MicroArray (TMA) of a mouse tumor panel (Ki67).

Masson’s trichrome staining on mouse lung

Detection of cartilaginous structures into the bronchial walls.

Pentachrome Movat staining on rat digestive system

Staining of stomach, small bowel and large bowel.

Von Kossa staining on human placenta

Von Kossa staining highlights calcium phosphates and carbonates in tissues (black staining). The counterstaining labels nuclei in red and cytoplasm in pink

HE alcian blue staining on rat digestive system

HE alcian blue staining highlights acid mucopolysaccharides and mucins in blue.

HE alcian blue staining on rat joint

Alcian blue staining highlights cartilage in blue.

PAS methenamine staining on rat kidney

PAS methenamine staining highlights the glomerular membranes (black staining).

Calleja staining on Tiger mosquito

Filaggrin immunohistochemistry on human skin

The filaggrin is an epidermal protein associated with the maintenance of skin moisture in the stratum corneum.

Masson trichrome staining on mouse kidney

Masson trichrome staining on mouse kidney

Hematoxylin eosin staining in mouse brain

Hematoxylin eosin staining of mouse glioma.
Immunostaining anti-CD31of human ureter

Immunogenicity characterization of human ureter in frozen block with CD31 immunostaining.

Immunostaining anti-CD31of human spinal cord

Immunogenicity characterization of human spinal cord with CD31 immunostaining.

Immunostaining anti-CD31 of human cerebellum

Immunogenicity characterization of human cerebellum in frozen block with CD31 immunostaining.

Hematoxylin eosin staining of mouse sternum

Hematoxylin eosin staining of mouse sternum in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).

Osmoregulatory cells immunostaining of bar (fish) gills

Osmoregulatory cells immunostaining of bar (fish) gills to study the polluant impact.
In situ hybridization (Marteilia) in oyster

Detection of DNA parasites localized in the digestive glands of oysters: Marteilia.
In situ hybridization (Bonamia) in oyster

Detection of DNA parasites localized in the gills of oysters: Bonamia.
Hematoxylin eosin – Toxicity evaluation in aquatic environment

Hematoxylin eosin – Morphological assesments on zebrafish gonads.
O safranin – Green light staining of linden bud

O safranin – Green light staining of linden bud to differenciate vegetal cell compartiments.
Masson’s trichrome staining on zebrafish

Assessment of the aquatic toxicity by analyzing the morphological changes in zebrafish gills.
β-Amyloid Immunolabeling on mouse brain

To reveal amyloid plaques by anti-β-Amyloid immunolabeling on mouse brain.
Cleaved caspase-3 immunolabeling on mouse liver

Mouse liver apoptosis evaluation by immunolabeling of cleaved caspase-3.
Rhodamin’s staining on mouse liver

Stain and quantification of copper deposits on mouse liver (use for WILSON’s disease).
Ki67 immunolabeling on human skin

Ki67 immunolabeling assesment of epiderm mitotic index.
Melan-A immunolabeling on human skin

Melan-A is a protein expressed by melanomas and by benign adult melanocyte cells. This labelling is used for quantifying the production of melanin.
CD31 immunolabeling on human skin

Mainly used to demonstrate the presence of endothelial cells, it can determine the degree of angiogenesis, for example.
Collagen IV immunolabeling on human skin

Collagen IV immunolabeling serves to determine the degree of elasticity of skin (efficiency test in cosmetic/dermatology).
Hematoxylin-eosin-saffron (HES) staining of mouse skin

HHES staining colors collagen fibers in yellow-orange.
Fontana Masson’s staining of human skin

Histological assesment of a pro/anti-pigmenting effect by melanin quantification.
Masson’s trichrome in mouse skin

Masson’s trichrome in mouse skin – Green light specificaly stain collagens.
Hematoxylin eosin staining on mouse skin

Hematoxylin eosin staining is use for evaluate morphologicals characters of skin.
In situ hybridization by ALU probe on settler

Characterization of an animal model of colitis in humanized mice.
Insulin immunolabeling on rat pancreas

Quantification of insulin by image analysis in a rat model for hypertension.
Toluidine blue staining on rat bladder

Violet Staining of mast cells.
Verhoeff's staining in rat lung

Verhoeff’s staining in rat lung. Highlights elastin fibers on histological sections.
Paragon staining in mouse joint

Paragon staining in mouse joint to show the destruction/reconstruction of cartilage in diseases cases.
Sirius red staining on human liver

Classification of different levels of hepatic fibrosis according to the amount of collagen (red).
CD68 immunostaining on rat brain

Characterization of inflammation in an animal model of glioma (C6 cells injection).
In situ hybridization with ALU probe on mouse brain

Tumors and micrometastasis detection in a glioma model.
Tyrosine hydroxylase immunolabeling on rat brain

Labeling of dopaminergic neurons in the substantia nigra.
Cresyl violet staining in mouse brain

Cresyl violet staining in mouse brain – Common protocol to stain nervous tissues.
Hematoxylin eosin staining in rat brain

Characterization of an animal model of glioma (C6 cells injection in the putamen).
HER2 immunolabeling in xenograft

HER-2 status characterization of xenografts by immunohistochemistry of HER-2.
α-SMA and CD31 immunolabeling on mouse/human xenograft

Characterization of angiogenesis in tumors (α-SMA in red and CD31 in brown).
Vimentin immunolabeling in xenograft

This histological marker of various potentially tumor tissues, is an ideal candidate for oncology diagnosis.

Cresyl violet staining in rat brain

Cresyl violet staining in rat brain to detect glioma.
Hematoxylin eosin staining of mouse lung

Hematoxylin eosin staining of mouse lung in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).

Hematoxylin eosin staining of mousemandibular lymph nodes – salivary glands

Hematoxylin eosin staining of mouse mandibular lymph nodes – salivary glands in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).

Hematoxylin eosin staining of mouse heart

Hematoxylin eosin staining of mouse heart in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).

Hematoxylin eosin staining of mouse spleen – thymus – pancreas

Hematoxylin eosin staining of mouse spleen – thymus – pancreas in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).

Liver - adrenal glands

Hematoxylin eosin staining of mouse liver – adrenal glands in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).

Hematoxylin eosin staining of mouse digestive system

Hematoxylin eosin staining of mouse stomac – duodenum – ileon – caecum – settler – rectum in the toxicity study in compliance with RITA.

Hematoxylin eosin staining of mouse tong – skeletal muscle

Hematoxylin eosin staining of mouse tong – skeletal muscle – sciatic nerves in the toxicity study in compliance with RITA (Registry of Industial Toxicology Animal-data).moelle-osseuse-multiplex