Exemples of achievements
Phospho-EGFR receptor quantification on tumor xenografts
The epithelial growth factor receptor (EGFR) is particularly over expressed in several tumour pathologies (breast tumours, carcinoma, etc.). When it is bound to the epidermal growth factor (EGF), it is partly responsible for cell division. It is therefore a signalling pathway very much exploited in the research for novel therapies.
We have developed an application for image analysis which aims to quantify the expression of phospho-EGFR. In this video, we show you how to quantify this receptor in a xenograft model and measure its expression level. One can thus obtain indications regarding the efficacy of the treatment tested.
Species : Human/Mouse
Tissue : Xenograft