Exemples of achievements
Species : rat
Sample : brain
Labeling : Tyrosine hydroxylase
Case study summary
Parkinson‘s 6-OHDA disease models: unilateral injection in the nigrostriatal pathway induces the loss of dopaminergic neurons in the substantia nigra and the degeneration of neuronal extensions in the striatum. In collaboration with Porsolt.
Spatial distribution and granulometry in xenograft
In this video, we present a method of image analysis making it possible to characterize the spatial distribution and particle size of tumour infiltration using ALU probe marking in xenografted mouse brains. The aim is to quantify the presence of micro metastases appearing after an injection of human tumour cells.